Perubahan Tekanan Darah Setelah Pemberian Air Rebusan Daun Kelor (Moringa Oleifera) Pada Penderita Hipertensi
Changes in Blood Pressure After Administration of Moringa (Moringa oleifera) Leaf Decoction in Patients with Hypertension
DOI:
https://doi.org/10.59585/bajik.v5i1.1598Keywords:
Daun Kelor, Hipertensi, Moringa Oleifera, Tekanan Darah, Terapi KomplementerAbstract
Hypertension is a major health problem associated with cardiovascular complications. Complementary herbal interventions, including Moringa oleifera, require clinical evaluation. Objective: To analyze changes in blood pressure after Moringa oleifera leaf decoction among patients with hypertension at Kademangan Public Health Center, Cianjur. Methods: A quasi-experimental one-group pretest-posttest design was used. Twenty-three participants were recruited using purposive sampling. Blood pressure was measured at baseline, weekly during six weeks of intervention, and after intervention. The Shapiro-Wilk test assessed normality; Wilcoxon signed-rank test compared pretest and posttest values, while the Friedman test assessed changes across eight measurement points. Results: Mean systolic blood pressure decreased from 183.48±15.63 mmHg to 135.91±15.19 mmHg, and diastolic blood pressure decreased from 95.74±4.38 to 83.61±4.62 mmHg. Wilcoxon testing showed significant pre-post differences for both systolic and diastolic blood pressure (both p<0.001). Friedman testing demonstrated significant changes across the eight time points (systolic χ²(7)=160.55; diastolic χ²(7)=140.15; both p<0.001). Conclusion: Blood pressure decreased significantly after the intervention, with a gradual downward pattern over six weeks.
References
Abd Rani NZ, Husain K, Kumolosasi E. Moringa genus: a review of phytochemistry and pharmacology. Front Pharmacol. 2023;14:1181845.
Arshad, M. T., Maqsood, S., Ikram, A., & Gnedeka, K. T. (2025). Recent perspectives on the pharmacological, nutraceutical, functional, and therapeutic properties of Moringa oleifera plant. Food Science & Nutrition, 13(4), e70134. https://doi.org/10.1002/fsn3.70134
Badan Kebijakan Pembangunan Kesehatan, Kementerian Kesehatan Republik Indonesia. Survei Kesehatan Indonesia (SKI) 2023. Jakarta: BKPK Kemenkes RI; 2024.
Charchar, F. J., Prestes, P. R., Mills, C., Ching, S. M., Neupane, D., Marques, F. Z., Sharman, J. E., Vogt, L., Burrell, L. M., Korostovtseva, L., Zec, M., Patil, M., Schultz, M. G., Renna, N. F., Islam, S. M. S., Hiremath, S., Gyeltshen, T., Chia, Y. C., Gupta, A., ... Tomaszewski, M. (2024). Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension. Journal of Hypertension, 42(1), 23–49. https://doi.org/10.1097/HJH.0000000000003563
Feitosa, A. D. M., Barroso, W. K. S., Mion, D., Jr., Nobre, F., Mota-Gomes, M. A., Jardim, P. C. B. V., Amodeo, C., Oliveira, A. C., Alessi, A., Pierin, A. M., et al. (2024). Brazilian guidelines for in-office and out-of-office blood pressure measurement—2023. Arquivos Brasileiros de Cardiologia, 121(4), e20240113. https://doi.org/10.36660/abc.20240113
Kementerian Kesehatan Republik Indonesia. Pedoman Nasional Pelayanan Kedokteran Tata Laksana Hipertensi Dewasa. Jakarta: Kementerian Kesehatan RI; 2023.
Leone A, Spada A, Battezzati A, Schiraldi A, Aristil J, Bertoli S. Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an updated review. Int J Mol Sci. 2024;25(3):1458.
Liu, R., Liu, J., Huang, Q., Liu, S., & Jiang, Y. (2022). Moringa oleifera: A systematic review of its botany, traditional uses, phytochemistry, pharmacology and toxicity. Journal of Pharmacy and Pharmacology, 74(3), 296–320. https://doi.org/10.1093/jpp/rgab131
McEvoy, J. W., McCarthy, C. P., Bruno, R. M., Brouwers, S., Canavan, M. D., Ceconi, C., Christodorescu, R., Daskalopoulou, S. S., Ferro, C. J., Gerdts, E., et al. (2024). 2024 ESC Guidelines for the management of elevated blood pressure and hypertension. European Heart Journal, 45(38), 3912–4018. https://doi.org/10.1093/eurheartj/ehae178
Moore, M. N., Atkins, E. R., Salam, A., Callisaya, M. L., Hare, J. L., Marwick, T. H., Nelson, M. R., Wright, L., Sharman, J. E., & Rodgers, A. (2019). Regression to the mean of repeated ambulatory blood pressure monitoring in five studies. Journal of Hypertension, 37(1), 24–31. https://doi.org/10.1097/HJH.0000000000001977
Pareek, A., Pant, M., Gupta, M. M., Kashania, P., Ratan, Y., Jain, V., Pareek, A., & Chuturgoon, A. A. (2023). Moringa oleifera: An updated comprehensive review of its pharmacological activities, ethnomedicinal, phytopharmaceutical formulation, clinical, phytochemical, and toxicological aspects. International Journal of Molecular Sciences, 24(3), 2098. https://doi.org/10.3390/ijms24032098
Rifkia V, Zahra RK, Kolib A. Effectiveness of giving Moringa oleifera leaf extract in reducing blood pressure: a systematic review. Journal of Research in Pharmacy and Pharmaceutical Sciences. 2023;2(2):78–86.
Salam, A., Atkins, E., Sundström, J., Hirakawa, Y., Ettehad, D., Emdin, C., Neal, B., Woodward, M., Chalmers, J., Berge, E., Yusuf, S., Rahimi, K., & Rodgers, A. (2019). Effects of blood pressure lowering on cardiovascular events, in the context of regression to the mean: A systematic review of randomized trials. Journal of Hypertension, 37(1), 16–23. https://doi.org/10.1097/HJH.0000000000001994
Samarin, M. M., Sheikhhossein, F., Khalilkhaneh, A. H., Ghaemi, S., Abbasi, A., Bazyar, H., Djafari, F., Dianati, Z., Khodashenas, S. M., Askari, G., & Amini, M. R. (2026). The effect of Moringa oleifera on body weight and blood pressure: A systematic review and meta-analysis of randomized controlled trials. Food Science & Nutrition, 14(5), e71899. https://doi.org/10.1002/fsn3.71899
Shin, J., Wang, J.-G., Chia, Y.-C., Kario, K., Chen, C.-H., Cheng, H.-M., Fujiwara, T., Hoshide, S., Huynh, M. V., Li, Y., et al. (2024). The HOPE Asia Network consensus on blood pressure measurements corresponding to office measurements: Automated office, home, and ambulatory blood pressures. Journal of Clinical Hypertension, 26(12), 1351–1361. https://doi.org/10.1111/jch.14729
Shalkur D, Dapar MP, Jimam NS. Clinical antihypertensive efficacy and safety of Moringa oleifera Lam. leaf: a systematic review. Journal of Pharmacy and Bioresources. 2025;22(1):45–58.
Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, et al. 2024 International Society of Hypertension global hypertension practice guideline. J Hypertens. 2024;42(2):185–245.
Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, et al. 2024 guideline for the management of hypertension. Hypertension. 2024;81(5):e45–e148.
Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, et al. Hypertension management: current evidence and future directions. Eur Heart J. 2024;45(9):825–846.
World Health Organization. Hypertension [Internet]. Geneva: World Health Organization; 2025 [cited 2026 Jul 4]. Available from: https://www.who.int/news-room/fact-sheets/detail/hypertension
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