Multivariate Analysis Of Infertility Risk Factors In Fertile Age Couples

Authors

  • Syahridayanti Syahridayanti Cokroaminoto University Makassar, Indonesia
  • Surtikanti Surtikanti ITEKES Muhammadiyah Kalimantan Barat, Indonesia
  • Marwan Ahmad Ganoko Bosowa University Makassar, Indonesia
  • Rezqiqah Aulia Rahmat Bosowa University Makassar, Indonesia

DOI:

https://doi.org/10.59585/ijhs.v4i1.1153

Keywords:

Infertility, Fertile Age Couples, Logistic Regression, Risk Factors

Abstract

Infertility is a reproductive health problem that impacts the biological, psychological, and social aspects of couples of childbearing age (PUS). Various factors such as age, body mass index (BMI), history of infection, hormonal disorders, and lifestyle are suspected to play a role in the occurrence of infertility. This study aims to analyze the risk factors for infertility in couples of childbearing age using a multivariate approach. The study used a case-control design with a sample of 120 respondents (60 infertility cases and 60 fertile controls). Data were collected through structured interviews and medical record reviews. Analysis was performed using multiple logistic regression to determine the dominant risk factors. The results showed that the wife's age ≥35 years (OR=3.8; p=0.002), a history of reproductive tract infections (OR=4.5; p=0.001), an abnormal BMI (OR=2.9; p=0.010), and the husband's smoking habit (OR=3.2; p=0.005) were significant risk factors for infertility. The dominant factor was a history of reproductive tract infections. It is concluded that infertility is multifactorial and requires a comprehensive approach in its prevention and treatment.

Downloads

Download data is not yet available.

Author Biographies

Syahridayanti Syahridayanti, Cokroaminoto University Makassar, Indonesia

Midwifery Study Program

Surtikanti Surtikanti, ITEKES Muhammadiyah Kalimantan Barat, Indonesia

Surtikanti

Marwan Ahmad Ganoko, Bosowa University Makassar, Indonesia

Faculty of Medicine

Rezqiqah Aulia Rahmat, Bosowa University Makassar, Indonesia

Faculty of Medicine

References

Agarwal A, et al. Male infertility. Lancet . 2015;385:164–178.

Anurogo, D., Rahmat, RA, & Pannyiwi, R. (2025). Identification of Endophytic Fungi in Traditional Medicinal Plants in South Sulawesi. JIMAD: Multidisciplinary Scientific Journal, 3(2), 77–82. https://doi.org/10.59585/jimad.v3i1.862

Boivin J, et al. International infertility prevalence. Hum Reprod . 2007;22:1506–1512.

CDC. Infertility overview. Atlanta; 2022.

Cunningham FG, et al. Williams obstetrics . 2018.

Darwis, A., Syahridayanti, S., Pratiwi, C., & Wahyuni, S. (2025). Touch Therapy Or Light Massage That Stimulates The Body To Release Endorphine Compounds (Endorphine Massage) For Labor In Mothers In Active Phase Of In-Partu With Pain In The First And Second Periods. International Journal of Health Sciences, 3(2), 193–199. https://doi.org/10.59585/ijhs.v3i2.643

Ganoko, MA, Saleh, MA, & Amiruddin, T. (2024). Characteristics of Coronary Heart Disease Patients Hospitalized at Dr. La Palaloi Maros Regional Hospital from January 2022 to December 2023. Barongko: Journal of Health Sciences, 3(1), 54–64. https://doi.org/10.59585/bajik.v3i1.471

Inhorn MC. Global infertility. Reprod Health . 2015;12:20.

Mascarenhas MN, et al. Global infertility rates. PLOS Med . 2012;9:e1001356.

Notoatmodjo S. Health research methodology . 2020.

Niederberger C. Male infertility. Nat Rev Urol. 2017;14:675–690.

Maheshwari A. Female age and fertility. Hum Reprod Update. 2008;14:59–68.

ASRM Practice Committee. Infertility definitions. Fertile Sterile . 2020;113:533–535.

Pannyiwi, R., Azis, MNSA, & Rahmat, RA (2025). Analysis of Nurses' Obstacles in Implementing Therapeutic Communication in Healthcare Environments. Barongko: Journal of Health Sciences, 4(1), 231–243. https://doi.org/10.59585/bajik.v4i1.921

Sharma R, et al. Lifestyle factors and infertility. Reprod Biol Endocrinol . 2013;11:66.

WHO. Infertility fact sheet. Geneva; 2023.

WHO. Sexual and reproductive health. Geneva; 2022.

Wahyuni, T., Achmad, VS, Pannyiwi, R., & Rahmat, R. A . (2025). The Relationship Between Nurse's Knowledge about Ventilators and Compliance in Preventing Ventilator - Associated Pneumonia (VAP) in the ICU. International Journal of Health Sciences, 3(4), 704–710. https://doi.org/10.59585/ijhs.v3i4.892

Zegers-Hochschild F, et al. International glossary. Hum Reprod . 2017;32:1786–1801.

Downloads

Published

2026-03-29

How to Cite

Syahridayanti, S., Surtikanti, S., Ganoko, M. A., & Rahmat, R. A. (2026). Multivariate Analysis Of Infertility Risk Factors In Fertile Age Couples. International Journal of Health Sciences, 4(1), 259–264. https://doi.org/10.59585/ijhs.v4i1.1153